Of Stroke Treatment, Algorithms, Trials, and Such

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Problems in design of stroke treatment trials.

Critical evaluation of the literature was use to identify remediable flaws in the design of clinical trials of stroke treatment. Trials of dexamethasone, dextran, and glycerol were reviewed. Available studies have in common major weaknesses in case selection (failure to exclude arteriolar strokes due to hemorrhage or lacunar infarction), and failure to estimate required sample size. Problems of...

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ژورنال

عنوان ژورنال: Mayo Clinic Proceedings

سال: 1994

ISSN: 0025-6196

DOI: 10.1016/s0025-6196(12)61383-4